HUMIRA Citrate-free:
redesigned with your patients in mind

HUMIRA (adalimumab) Citrate-free is available to all indicated patients in the United States. HUMIRA Citrate-free features the same safety and efficacy profile of HUMIRA, with less pain immediately after injection.1,2

Changes they can see*

Thinner needle (29 gauge vs 27 gauge)2

50% less volume1

The same therapeutic amount of HUMIRA is now injected in half the volume (for the HUMIRA 40-mg dosage form, the volume is 0.4 mL instead of 0.8 mL)

Modifications to the Pen1

The HUMIRA Citrate-free Pen now has a larger viewing window and white numbers on the Pen caps

Revised packaging

HUMIRA Citrate-free comes in a blue box

HUMIRA pen and prefilled syringe

Changes they can't see*

Less pain immediately following injection2†

No citrate buffers1,2

Sodium citrate, known to cause pain, and other inactive ingredients have been removed3-6

Needle cover not made with natural rubber latex1

For both the HUMIRA Pen and prefilled syringe

Self-administration considerations

Before HUMIRA is self-injected, instruct patient on proper injection technique and monitor as necessary. Refer patient to Medication Guide for proper storage.

*The instructions for storing HUMIRA Citrate-free are not affected by the removal of inactive ingredients, change in volume, or modifications to the Pen. Although the injection may feel different, patients should continue to follow proper injection technique.

Injection site pain immediately following injection as measured using a 0-10 cm Visual Analog Scale: HUMIRA 40 mg/0.4 mL vs HUMIRA 40 mg/0.8 mL.