HUMIRA is approved for the treatment of moderate
to severe
hidradenitis suppurativa (HS) in patients
12 years of age and older.

A POSSIBLE CAUSE
OF HS

Not an actual HS patient

Recognizing
HS

A Possible
Cause

The Role
of HUMIRA

Partnering With a
Dermatologist

Looking to
treat with
HUMIRA?

What Causes HS?

The exact cause is unknown.

Misconceptions about hidradenitis suppurativa and its causes may lead to delays in diagnosis and appropriate management. It is important to understand that HS is not a disorder of the sweat glands, and it is not caused by poor hygiene or infection, although secondary infections can occur.2-4

While the exact cause of HS is unknown, HS is thought to begin deep within the body, before the physical symptoms manifest just underneath and on the surface of the skin. HS presents with systemic inflammation, driven by proinflammatory cytokines such as TNF-α (tumor necrosis factor-alpha). Overexpression of TNF-α plays a key role in fueling HS inflammation.3,5

In one study, HS lesions expressed 5 times more TNF-α than normal skin.6

Graphic showing HS lesions.

TNF-α PLAYS A ROLE IN MANY CHRONIC, IMMUNE-MEDIATED CONDITIONS1,6,10

RHEUMATOLOGY

Psoriatic arthritis
Rheumatoid arthritis
Ankylosing spondylitis
Juvenile idiopathic arthritis
Uveitis

GASTROENTEROLOGY

Adult ulcerative colitis
Pediatric ulcerative colitis
Adult Crohn’s disease
Pediatric Crohn’s disease

DERMATOLOGY

Plaque psoriasis
Psoriatic arthritis
Hidradenitis suppurativa

OPHTHALMOLOGY

Uveitis

Partner with a dermatologist

Dermatologists with experience in managing HS are key partners in care.

I refer my moderate to severe patients to a dermatologist. My relationship as an OB/GYN stays the same, so the dermatologist and I partner in the treatment of HS patients.

– Insight from an OB/GYN

Looking to prescribe HUMIRA?

Watch “Navigating the Unknown”

Reflections on HS from HS-treating dermatologists, a pediatrician, and actual patients.

Members of the HS care team, including HS-treating dermatologists and a pediatrician, discuss the importance of timely identification and appropriate treatment of HS. Actual HS patients discuss the impact HUMIRA has had on their journey with HS.

Video thumbnail of navigating the unknown.

Next:

The Role of HUMIRA